Abstract：Objective: To evaluate the clinical value of double phase 99mTc-MIBI imaging in diagnosing hyperparathyroidism. Methods: Forty-four patients with highly suspected hyperparathyroidism underwent double phase 99mTc-MIBI imaging. Abnormal increase radioactivity in delay imaging stood for positive index. Imaging material were evaluated according to final clinical results and compared with ultrasound or CT. Results: In 44 patients, 33 hyperparathyroidism were proven, including 31 adenomas(ectopic 1), 1 hyperplasia and 1 carcinoma. The sensitivity and specificity of diagnosis were 90.9%, 100%, respectively. The accuracy of double phase 99mTc-MIBI imaging was 93.2%. The sensitivity and specificity of ultrasound were 70%, 77.3%, respectively. The sensitivity of CT was 60%. The results showed that double phase 99mTc-MIBI imaging was superior to ultrasound and CT(P<0.05). Conclusion: Double phase 99mTc-MIBI imaging could accurately diagnose hyperparathyroidism. It is an important localizing method for preoperation which is worthy of generating.
2006, Vol. 17 
