Abstract:Objective: To investigate the differential diagnostic value of common subtypes of renal cell carcinoma using CT urography(CTU). Methods: The images of CTU including characteristic manifestations of plain scanning and three-dimensional reconstruction in 150 cases of renal cell carcinoma proved by pathology were analyzed retrospectively and the CT value of different renal cell carcinoma in each period were compared. Results: There were 109 cases of clear cell renal cell carcinoma, 21 cases of papillary renal cell carcinoma, 8 cases chromophobe renal cell carcinoma, 9 cases of unclassified renal cell carcinoma and 3 cases of multilocular renal cell carcinoma. The above subtypes of renal cell carcinoma demonstrated characteristic features. Clear cell renal cell carcinoma exhibited inhomogeneous low density and hypervascular. Papillary renal cell carcinoma exhibited inhomogeneous high density and hypovascular. Chromophobe renal cell carcinoma was relatively homogeneous low density and hypovascular. Unclassified renal cell carcinoma is similar to clear cell renal cell carcinoma. Multilocular renal cell carcinoma presented as a multilocular cystic mass lacking an expansile nodule. The CT value of papillary is higher than clear cell renal cell carcinoma, chromophobe renal cell carcinoma and unclassified renal cell carcinoma(P<0.05) on plain scanning. The CT value of the latter three is indistinctive and the CT value of the above four subtypes is higher than multilocular renal cell carcinoma. There is no difference of clear cell renal cell carcinoma and uncalssified renal cell carcionma in CT value in arterial phase and venous phase(P>0.05), but CT value of them is higher than papillary renal cell carcinoma and chromophobe of which are indistinctive(P>0.05). The CT value of multilocular renal cell carcinoma is lower than the others(P<0.05) in arterial phase and venous phase. The CT value of multilocular renal cell carcinoma is lower than the others(P<0.05) of which are indistinctive(P>0.05) in delayed phase. Conclusion: Common subtypes of renal cell carcinoma demonstrated characteristic features in CTU and it is helpful for differentiation.