CT and MRI features of ganglioglioma and clinical pathological analysis
HUANG Qing-ling1, LIU Wen1, CAI Zong-yao1, ZHANG Zong-jun2, LU Guang-ming2
1. Department of Radiology, Nanjing Medical University Affiliated Brain Hospital, Nanjing 210029, China;2. Department of Medical Imaging, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China
Abstract：Objective: To better characterize and report the images of the ganglioglioma(GG) in a series of 17 cases. Methods: Clinical and pathologic features of all cases were retrospectively studied. Results: This group included 17 patients. All cases demonstrated solitary lesion. Fifteen lesions located in supratentorial region, 2 lesions situated in the subtentorial region. Among them, 6 lesions located in the temporal lobe, 5 lesions located in the frontal lobe, 2 lesions located in the parietal lobe, 4 lesions located in the corpus callosum, frontal-temporal lobe, left cerebellum and medulla-cervical cord respectively. CT scan of 3 cases disclosed moderate hypodense lesion, 1 isodense, without peritumoral edema, 1 lesion with bone resorption. On MRI 7 lesions displayed gyriform granulose, 5 lesions were elliptical, the rest were irregular in shape. There were 6 mural nodule in 17 lesions. On T1WI the lesions appeared to be hypointense; T2WI, hyperintense or mixed signal; and absence of contrast enhancement. On T2 fluid attenuated inversion recovery weighted images, the margin and the mural nodule of the lesion appeared to be hyperintense. On DWI the lesions appeared to be isointense to hypointense, while the apparent diffusion coefficient(ADC) value was high. Conclusion: The typical neuroradiologic aspect of GG may be helpful for the diagnosis preoperatively.
2008, Vol. 19 
