Abstract：To discuss the changes of superior mesenteric venous perfusion(SMVP) and splenil venous perfusion(SpVP) respectively before and after cholestatic cirrhosis by CT perfusion of portal vein in dogs. Methods: Only partial liver was involved in this cholestatic cirrhosis model. Twelve dogs survived from the process of model building. By selective catheterization in superior mesenteric artery and splenic artery by femoral Seldinger technique, SMVP and SpVP were available after portal CT perfusion. SMVP and SpVP of the normal part and cirrhotic part, before and after cirrhosis, were compared respectively. Results: SMVP and SpVP of the involved lobe decreased significantly from those of normal state, and the decrease ratio of SMVP differed significantly from that of SpVP(P=0.003). After model building, there was significant difference between SMVP and SpVP of the involved lobe and those of the normal lobe, and the decrease ratio of SMVP differed significantly from that of SpVP(P=0.001). Conclusion: After cholestatic cirrhosis, SMVP and SpVP decreased significantly, and the decrease of SMVP contributed more.
孙洪赞;郭启勇;廖 伟;卢再鸣;高玉颖. 肝硬化前后肠系膜上静脉和脾静脉CT灌注量改变的实验研究[J]. , 2008, 19(10): 701-704.
SUN Hong-zan;GUO Qi-yong;LIAO Wei;LU Zai-ming;GAO Yu-ying . Changes of superior mesenteric venous perfusion and splenic venous perfusion after hepatic cirrhosis: experimental study in canines. , 2008, 19(10): 701-704.
2008, Vol. 19 
