Abstract： Objective: To evaluate the clinical value of X-ray attenuation correction for myocardial imaging in SPECT/CT. Methods: Total 65 cases, 35 cases(Group 1), with no coronary artery disease by clinical history, ECG, ultrasound and other necessary clinical examinations; 30 patients(Group 2) with coronary artery disease. All underwent 99mTc-MIBI myocardial perfusion tomography imaging and X-ray attenuation correction and were compared with their angiograms. Results: ①The uptake ratios of inferior and posterior wall in Group 1 and Group 2 increased from (77.0±4.77)% and (76.0±5.7)%, (31±4.3)％ and (35±5.5)％ without X-ray attenuation correction to (85.0±4.5)% and (83.0±5.2)%, (38±5.1)％ and (42±5.5)% with X-ray attenuation correction(P<0.001), respectively. ②With qualitative analysis, Group 1: 82.8% subjects showed obvious improvement in the defects in inferior and posterior wall; 14.3% subjects with medium-level improvement. Group 2: 73.7% subjects showed improvement. ③The coherence of myocardial perfusion angiographic images of Group 1 and Group 2 after X-ray attenuation correction improved to 8.6%, 15.4% separately. Conclusion: X-ray attenuation correction in SPECT/CT is a simple and valid method. It corrects most of the attenuation artifacts in myocardial perfusion imaging, especially in the inferior and posterior wall. It helps to avoid the false positive diagnosis and improve the diagnostic confidence of nuclear cardiologists. It is important for coronary artery disease especially with myocardial perfusion images.
闫新慧. 心肌灌注SPECT显像采用X线CT衰减校正的临床应用[J]. , 2010, 21(6): 388-391.
YAN Xin-hui. The value of X-ray attenuation correction for myocardial perfusion imaging. , 2010, 21(6): 388-391.
2010, Vol. 21 
