Abstract:Objective: To improve the awareness of the CT appearances and clinical presentations of mesenchymal hamartoma of the liver(MHL). Methods: Clinical data, pre- and post-enhanced CT images of 5 cases of MHL were retrospectively reviewed from January 2005 to June 2011 in our hospital. Results: In these 5 cases, there were 3 boys and 2 girls. All of the lesions were solitary, with 4 in the right lobe and one in the left lobe. The biggest size of the mass was 16.6 cm×11.9 cm, while the smallest size was 5.1 cm×4.1 cm. Pre-enhanced CT scan showed the mass was a mixture of cysts cavities and solid septations. Post-enhanced CT scan showed an increased enhancement of the septa, while the cysts had no enhancement. Conclusion: Mesenchymal hamartoma is a kind of rare benign tumors which arise from liver in children. As its main imaging study method, CT scan has some specific features: Pre-enhanced CT scan shows a mixed mass which usually locates in right lobe, while post-enhanced CT scan shows an enhancement of the septa. Pathological examination is necessary for the final results.