Abstract：Objective: To evaluate the value and the accuracy of transabdominal sonography(TAS) and three-dimensional transvaginal ultrasound(3D-TVS) examination in the diagnosis of fetal malformations during first trimester and second trimester. Methods: We summarized and analyzed retrospectively the ultrasonic image features of 26 cases, wihch were diagnosed as fetal structural abnormalities by TAS and 3D-TVS at 11～14 weeks gestation, then confirmed at second trimester or by postmortem after induction. Results: Twenty-four cases were followed up, and 2 cases lost contact. Only one with conjoined twins was missed at 11 weeks of gestation. Other fetal structural abnormalities were consistent with the TAS and 3D-TVS findings. Conclusions: TAS and 3D-TVS examination have important value in the early detection of fetal structural abnormalities. Standardization of the examination is the key to reduce misdiagnosis.
2012, Vol. 23 
