The reliability of 3D TOF MRA for preoperative assessment of intracranial vascular stenosis by 3.0T MR system
SUN Jing1, ZHANG Shi-de2, WEI Yong-bing1, BAI Lin-gang3
1. Department of MRI, Zaozhuang Mining Group General Hospital, Zaozhuang Shandong 277899, China;2. Department of Radiology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150000, China;3. Department of CT, Liaocheng Tumor Hospital, Liaocheng Shandong 252000, China
摘要目的：探讨3.0T 3D TOF MRA对颅内血管狭窄术前评估的可靠性。方法：哈尔滨医科大学附属二院30例颅内动脉狭窄患者，均行3.0T 3D TOF MRA和旋转数字减影血管成像（DSA）检查。分析30例患者的450个血管片段。以DSA为诊断标准，以有无狭窄、轻度狭窄（10%~＜50%）、狭窄50%、70%、100%为判定点计算敏感性、特异性、阳性预测值（PPV）及阴性预测值（NPV）。结果：共发现115段病变血管，MRA发现狭窄的敏感性、特异性分别为87.0%和99.7%；以50%为界点分别是86.7%和99.5%，PPV 92.9%和NPV 99.1%；以70%为界点分别是95.5%、99.5%、PPV 91.3%和NPV 99.5%。8处闭塞MRA诊断出7处，假阳性、假阴性各1处（分别是基底动脉和椎动脉颅内段）。28段（24.6%）高估，7段低估。结论：对于判定50%、70%颅内动脉狭窄，3.0T 3D TOF MRA与旋转DSA相比具有较高的敏感性及特异性，可作为支架置入术前一种有效的检查手段。
Abstract：Objective: To explore the reliability of 3D TOF MRA on 3.0T MR system for preoperative assessment of intracranial vascular stenosis. Methods: Thirty patients with intracranial arterial stenosis in the 2nd Hospital Affiliated to Harbin Medical University, who received both 3D TOF MRA on a 3.0T MR system and rotational digital subtraction angiography examinations. 450 vascular segments of the 30 patients were analysed. Without stenosis, mild stenosis(10%~＜50%), stenosis of 50%, 70%, 100% as decision point to calculate sensitivity, specificity, positive predictive value(PPV) and negative predictive value(NPV) of MRA. Results: Compared to DSA, 115 lesions were detected, the sensitivity and specificity were 87.0% and 99.7% for MRA in detecting stenosis. Take 50% as the critical point. The sensitivity and specificity was 86.7% and 99.5% respectively, the PPV was 92.9% and the NPV was 99.1%. Take 70% as the critical point the sensitivity and specificity was 95.5%, 99.5% respectively, PPV 91.3% and NPV 99.5%. MRA diagnosed 7 in the eight occlusions. One false positive and one false negative(that was stenosis of the basilar artery and intracranial segment of the vertebral artery). Twenty-eight(24.6%) segments were overestimated, 7 segments were underestimated. Conclusion: To determine 50% and 70% intracranial arterial stenosis, 3.0T 3D TOF MRA has high sensitivity and specificity compared to rotational DSA, and can be used as an effective means in pre-stenting surgery.
孙 静;张士德;魏永兵;白林刚. 3.0T 3D时间飞跃法磁共振颅内血管成像用于介入术前评价的可靠性研究[J]. , 2013, 24(3): 153-158.
SUN Jing;ZHANG Shi-de;WEI Yong-bing;BAI Lin-gang. The reliability of 3D TOF MRA for preoperative assessment of intracranial vascular stenosis by 3.0T MR system. , 2013, 24(3): 153-158.
2013, Vol. 24 
