Evaluation of endocardial and epicardial rotation based on the concept of space-time in chronic kidney disease patients
GUO Jia-bao1, DONG Bei-li2
1. Department of Ultrasonography, First Affiliated Hospital of Zhejiang Traditional Chinese Medical University, Hangzhou 310006, China; 2. Zhejiang Provincial Hospital of TCM, Hangzhou 310006, China
Abstract：Objective: To discuss the change of endocardial rotation angle and epicardial rotation angle in different phases by two-dimensional speckle tracking technology(STI) on patients with chronic kidney disease(CKD), we can evaluate cardiac function in patients with different stages of CKD from two aspects of time and space, and know its initial change in different planes and phases at the same time. Methods: Fifty patients with CKD were included. Among them stage 1～3 were assigned as CKD group 1, stage 4, 5 were assigned as CKD group 2. Each group included 25 cases. Twenty-five normal patients were in control group. The mean rotation angle of endocardium and epicardium of the three groups were obtained at each phase using STI. Results: ①During isovolumic contraction period, the rotation angle of endocardium and epicardium in both the basal and apical cardiac planes in CKD 1 and CKD 2 had no significant change. ②During ejection period, the rotation angle of endocardium in both the basal and apical cardiac planes in CKD 1 and CKD 2 were decreased; The rotation angle of epicardium in both basal and apical cardiac planes in CKD 2 were decreased. ③At the end of isovolumic diastole, the rate of endocardial untwisting in both basal and apical planes in CKD 1 and CKD 2 reduced significantly; The rate of epicardial untwisting in basal plane in CKD 1 and CKD 2 reduced at the same time. Conclusions: STI has a potential ability to evaluate when and where the heart function have changed first in patients with CKD by measuring the rotation of endocardium and epicardium of left ventricle．
郭家宝;董蓓莉. 基于时空概念研究慢性肾脏病患者心内外膜的旋转[J]. , 2013, 24(10): 691-694.
GUO Jia-bao;DONG Bei-li. Evaluation of endocardial and epicardial rotation based on the concept of space-time in chronic kidney disease patients. , 2013, 24(10): 691-694.
2013, Vol. 24 
