Abstract：Objective: To improve the diagnosis accuracy of ovarian sertoli-leydig cell tumor(SLCT), by exploring the MRI features. Materials and Methods: The MR images and clinicopathological characteristics were analysed in five cases with SLCT verified by surgery and pathology retrospectively. Results: The ages of the five cases ranged from 26 to 64 years old, three presenting signs of defeminization such as menstrual irregularities, amenorrhea and infertility, one presenting signs of masculinization such as hirsutism, acne and clitoromegaly, one complainting postmenopausal vaginal bleeding, and four cases with abdominal mass. The secrum testosterone was increased in all 5 cases. On MR, all 5 cases were unilateral with 2 in the right and 3 in the left. Four lesions were solid of round or oval shape with tiny cysts in 2 lesions. The solid components were hypointense on T1WI and slightly hyperintense on T2WI, hyperintense on DWI and hypointense on apparent diffusion coefficient map. The time signal intensity curve(TIC) of the solid regions showed sharp peak-plat form in dynamic contrast enhanced(DCE) MR imaging. One tumor was lobulated with multilobular cyst and nodular solid portion. The cyst was hypointense on T1WI and hyperintense on T2WI, while the solid part was hypointense on T1WI, slightly hyperintense on T2WI, and hyperintense on DWI. On histopathology, three SLCT cases were well differentiated, one was moderately differentiated and one was poorly differentiated. Immunohistochemically, all 5 cases were positive with inhibin and vimentin, and negative with epithelial membrane antigen(EMA). Conclusion: Ovarian SLCT demonstrates some characteristics on MR imaging, which will improve diagnosis accuracy combined with clinical features, and the final diagnosis usually depends on pathology.
方如旗，周作福，陈霞平，马 宏，潘地铃. 卵巢支持-间质细胞瘤的MR表现与临床病理对照分析[J]. 中国临床医学影像杂志, 2017, 28(7): 516-520.
FANG Ru-qi, ZHOU Zuo-fu, CHEN Xia-ping, MA Hong, PAN Di-ling. Analysis of MR imaging and clinicopathological characteristics of ovarian sertoli-leydig cell tumor. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(7): 516-520.
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