Abstract：Objective: To investigate the value of MR diffusion weighted imaging(DWI) in the differential diagnosis of high and low-grade meningioma. Methods: Thirty-one patients with low-grade meningioma(WHO Ⅰ) and 25 patients with high-grade meningioma(WHO Ⅱ~Ⅲ) were enrolled in this study, the DWI data were retrospectively analyzed. The patients were divided into low-grade group and high-grade group, and ADC values were measured separately. The difference in ADC value was compared between two groups. The ROC curve was drawn, and the cutoff value for the high-grade meningioma detection was determined. Results: The ADC value of high and low-grade meningioma was (0.72+0.10)×10-3 mm2/s, (0.93+0.12)×10-3 mm2/s respectively, the ADC value of high-grade meningioma was significantly lower than that of low-grade meningioma, the difference was statistically significant(t=7.30, P<0.01); ROC curve analysis showed that the ADC value for the best critical point of diagnosis for high-grade meningioma was 0.83×10-3 mm2/s. The sensitivity was 84%, specificity was 80.6%, accuracy was 82.1%. Conclusion: MR DWI ADC has high value in the differential diagnosis of high and low-grade meningioma, which can provide more information for treatment and prognostic evaluation
牟东景，程军林. 磁共振扩散加权成像对高、低级别脑膜瘤的鉴别诊断价值[J]. 中国临床医学影像杂志, 2017, 28(11): 761-763.
MU Dong-jing, CHENG Jun-lin. Value of MR DWI in differential diagnosis of high and low-grade meningioma. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(11): 761-763.
