Abstract：Objective: To analyze left ventricular diastolic energy loss(EL) in patients with grade Ⅰ diastolic dysfunction using vector flow mapping(VFM), and to explore its clinical value in assessment of left ventricular diastolic function. Methods: Forty-seven healthy volunteers from our hospital were include in the study. They were divided into two groups: 24 with E/A>1, e’/a’ >1(normal diastolic function), 23 with E/A<1, e’/a’<1(grade Ⅰ diastolic dysfunction). Standard apical 3-chamber dynamic color Doppler images were recorded in VFM mode, and DSA-RS1 workstation was used for off-line analysis. The difference of average diastolic EL was compared between the two groups. Results: During diastole, the EL in left ventricle will appear two peaks, one is in the rapid filling phase(peak1) and the other is in the atrial contraction phase(peak 2). Compared with the E/A>1 group, peak1 was obviously decreased in E/A<1 group((27.36±13.91) J/(m3·s) vs (12.37±9.33) J/(m3·s), P<0.001).The EL value of peak2 was shown no statistical significance. The average diastolic EL for normal diastolic function group and grade Ⅰ diastolic dysfunction group were ((10.43±3.84) J/(m3·s) and (7.66±4.12) J/(m3·s), respectively, with a significant difference between two groups(P<0.05). Conclusions: There was a significantly difference of left ventricular EL in adults between normal diastolic function group and grade Ⅰ diastolic dysfunction group, EL might be a sensitive index for the evaluation of diastolic dysfunction.
朱晓丽，徐 磊，刘丽文，孙 超，赵 丹. VFM评价Ⅰ级舒张功能减低左室舒张期能量损耗的初步研究[J]. 中国临床医学影像杂志, 2017, 28(11): 802-804.
ZHU Xiao-li, XU Lei, LIU Li-wen, SUN Chao, ZHAO Dan. An initial study of left ventricular diastolic energy loss in patients with
grade Ⅰ diastolic dysfunction using vector flow mapping. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(11): 802-804.
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