The correlative study between carotid plaque and volume of acute cerebral infarction
LIU Ya-bao1, JI Sheng-zhang2, ZHANG Bo-sheng1, JIA Fu-yan1
1. Department of Radiology, Tianjin Port Hospital, Tianjin 300456, China;
2. Department of Radiology, the Fourth Central Hospital of Tianjin, Tianjin 300140, China
Abstract：Objective: Through using multi sequence high resolution 3.0T MRI, classifying the carotid plaque, measuring plaque burden and analyzing its composition, to investigate the correlation of carotid artery plaque typing, carotid artery plaque burden and acute cerebral infarction. Methods: We enrolled sixty-five patients who had acute cerebral infarction to have MRI examination for head and bilateral carotid arteries within seven days through using Philips Intera Achieva 3.0T MRI(the skull sequences include T1WI, T2WI, FLAIR and DWI. Carotid arteries sequences include T1WI, T2WI, 3D time of fight and MP RAGE). Then we measured the volume of acute cerebral infarction in DWI. According to the MRI classification criteria of the artery plaque established by Cai Jianming etc, we used the software of CASCADE to classify the plaque and analyze its composition, measure the lumen area of carotid artery and total vascular area, calculate the WA and NWI, measure the lipid core volume in carotid plaque. Results: ①The incidence of carotid artery Ⅳ~Ⅴ and Ⅵ type plaque and the lipid core in plaque, the average tube wall area, the NWI of ischemic side carotid artery wall, all items of them were higher than that of non ischemic side. The difference was statistically significant(P<0.05). ②The NWI of carotid artery in ischemic side and the lipid core volume with the volume of acute cerebral infarction on the same side have strong positive correlations(P<0.05). Conclusion: The carotid atherosclerotic plaque is closely related to the occurrence of acute cerebral infarction. Through the 3.0T MR, the images displayed perfectly the composition of carotid plaque, carotid artery plaque typing, the quantitative measurement of carotid artery wall burden and the volume of the interior plaque component. Consequently, providing assistance to predict the occurrence of cerebral ischemia and monitor the development of the illness.
刘雅宝1，纪盛章2，张伯生1，贾福艳1. 颈动脉斑块与急性脑梗死体积的相关性研究[J]. 中国临床医学影像杂志, 2018, 29(3): 153-157.
LIU Ya-bao1, JI Sheng-zhang2, ZHANG Bo-sheng1, JIA Fu-yan1. The correlative study between carotid plaque and volume of acute cerebral infarction. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(3): 153-157.
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