Abstract：Objective: To evaluate the use of 18F-fluorodeoxyglucose(FDG) PET/CT in recurrence and metastasis of breast cancer. Methods: Thirty-seven patients after operation underwent 18F-FDG PET/CT whole body imaging for evaluation of recurrent breast cancer and metastasis. Visual and semiquantitative methods(standard uptake value, SUV) were used to analyze the images. The results of PET/CT imaging were compared with those of pathology or CT. Results: Twenty-seven malignant recurrent breast lesions in thirty-seven resected breast cancers detected by this modality were proven histopathology, biopsy, cytological examination, and clinical follow-up. Among the twenty-seven malignant breast lesions, the diagnostic sensitivity of PET/CT and CT imaging were 96.30% and 62.96% respectively. There were statistical differences in sensitivity between PET/CT and CT(χ2=9.247, P<0.05). Fourteen patients with breast cancer underwent PET/CT at 2 time points. Recurrence and metastasis were diagnosed in 9 patients, and all of their SUVs increased at time 2. Conclusions: 18F-FDG PET/CT makes the location and characterization of the lesions more accurate, and it is a useful diagnostic modality in the diagnosis of recurrent and metastatic breast cancer.
孙 琳;高再荣;张永学;贾 清;吴志坚;常 伟. 18F-FDG PET/CT、CT在乳腺癌治疗疗效评估中的对比研究[J]. , 2007, 18(10): 689-692.
SUN Lin;GAO Zai-rong;ZHANG Yong-xue;JIA Qing;WU Zhi-jian;CHANG Wei. Comparative study of 18F-FDG PET/CT and CT in evaluating curative effect of breast cancer. , 2007, 18(10): 689-692.
2007, Vol. 18 
