The value of 1.5T MR apparent diffusion coefficient ratio in the diagnosis of tongue cancer
ZHENG Xue-wei1, DING Jun1, LIU Shuo1, GUAN Yu-yao1, LI Tong1, FENG Yan2, FU Wei-guang2, YU Bao-ting1
1. Department of Radiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China;
2. Department of Radiology, Jilin Provincial People’s Hospital, Changchun 130021, China
Abstract:Objective: To evaluate the value and correlation of the ratio of apparent diffusion coefficient(ADC) of tongue lesions and surrounding normal glands in the diagnosis, pathological grading and staging of tongue cancer. Methods: Sixty patients with tongue lesions confirmed by surgical pathology in China-Japan Union Hospital of Jilin University from March 2017 to March 2019 were collected. Routine MRI and DWI scanning were performed before operation, and the ADC values of lesions and surrounding glands were measured and the ADC ratio was calculated. Results: ①There were 40 cases of tongue cancer and 20 cases of tongue benign lesions. The ADC ratio of tongue cancer was -0.13±0.17 and that of tongue benign lesions was 0.09±0.10, and the difference between the two ratios was statistically significant(t=5.129, P<0.05). ②The ADC ratio of the highly differentiated group was 0.02±0.07, the ADC ratio of the moderately differentiated group was -0.14±0.17, and the ADC ratio of the low-differentiated group was -0.26±0.09. There were statistically significant differences among the three groups(F=3.593, P=0.047). ③The ADC ratio of the advanced tongue cancer group(T3+T4) was -0.20±0.13, which was lower than that of the early tongue cancer group(Tis+T1+T2), the ADC ratio of the early tongue cancer group was 0.00±0.17(t=3.314, P=0.03<0.05). The difference between T4 and T1 and T2 was statistically significant(P<0.05), while no significant difference was found in other pairwise comparisons(P>0.05). Conclusion: The apparent diffusion coefficient ratio can provide reference for the differential diagnosis of benign and malignant tongue lesions and the pathological classification and staging of tongue cancer, and has important clinical significance.
郑雪微1,丁 军1,刘 硕1,管玉瑶1,李 佟1,冯 艳2,付卫光2,于保婷1. 1.5T磁共振表观弥散系数比值对舌癌的诊断价值[J]. 中国临床医学影像杂志, 2020, 31(4): 243-247.
ZHENG Xue-wei1, DING Jun1, LIU Shuo1, GUAN Yu-yao1, LI Tong1, FENG Yan2, FU Wei-guang2, YU Bao-ting1. The value of 1.5T MR apparent diffusion coefficient ratio in the diagnosis of tongue cancer. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(4): 243-247.
[1]左志超,张卫,邓文娟,等. ADC比值法对鉴别腮腺良恶性病灶的诊断价值[J]. 临床放射学杂志,2018,37(1):32-36.
[2]廖敏,张立力,柯亚娟,等. 舌癌扩大切除前臂桡侧皮瓣移植修复术的压疮防护策略[J]. 海南医学,2017,28(22):3773-3776.
[3]任振虎,吴汉江. 颈部淋巴结包膜外侵犯的研究现状[J]. 实用口腔医学杂志,2012,28(4):514-517.
[4]孙小雅,严汉兴,贺莎,等. 舌癌多种治疗方式的临床疗效比较[J]. 中南医学科学杂志,2018,46(1):16-19.
[5]鄢灵君,邱宇,陈法,等. 膳食因素与吸烟者和非吸烟者舌癌发病的关系[J]. 卫生研究,2017,46(2):189-195.
[6]Koo K, Barrowman R, McCullough M, et al. Non-smoking non-drinking elderly females: a clinically distinct subgroup of oral squamous cell carcinoma patients[J]. Int J Oral Max Surg, 2013, 42(8): 929-933.
[7]Martínez-Sánchez JM, Sureda X, Fu M, et al. Secondhand smoke exposure at home: assessment by biomarkers and airborne markers[J]. Environ Res, 2014, 133(2): 111-116.
[8]Wade J, Smith H, Hankins M, et al. Conducting oral examinations for cancer in general practice: what are the barriers?[J]. Fam Pract, 2010, 27(1): 77-84.
[9]裴宇文,杨光明,曾春光,等. 磁共振对舌癌的诊断与分期的作用[J]. 实用癌症杂志,2017,32(9):1563-1565.
[10]Morani AC, Elsayes KM, Liu PS, et al. Abdominal applications of diffusion-weighted magnetic resonance imaging: Where do we stand[J]. World J Radiol, 2013, 5(3): 68-80.
[11]Filli L, Wurnig MC, Luechinger R, et al. Whole-body intravoxel incoherent motion imaging[J]. Eur Radiol, 2015, 25(7): 2049-2058.
[12]林军,张志炎,郑攀丰,等. MR弥散加权成像表观弥散系数在前列腺疾病诊断中的应用[J]. 中国CT和MRI杂志,2019,17(2):50-52.
[13]Yuen S, Yamada K, Goto M, et al. Microperfusion-induced elevation of ADC is suppressed after contrast in breast carcinoma[J]. J Magn Reson Imaging, 2009, 29(5): 1080-1084.
[14]高永伟,牛广明,韩晓东. 3.0T磁共振诊断直肠癌ADC值与肿瘤分化程度的相关性分析[J]. 中国医疗前沿,2012,7(6):7-8.
[15]Razek AA. Diffusion-weighted magnetic resonance imaging of head and neck[J]. J Comput Assist Tomogr, 2010, 34(6): 808-815.
[16]王亚婷,朱艳,陆洋,等. 表观弥散系数平均值及最小值与肝癌病理学特征的相关性研究[J]. 中国临床医学影像杂志,2017,28(11):805-809.