Abstract：Objective: To investigate the diagnostic value of diffusion kurtosis imaging(DKI) in head and neck lymphoma. Methods: The clinical data of 114 cases of head and neck lymphoma(neck lymphoma group), 97 tumor patients with neck lymph node metastasis(lymph node metastasis group) and 82 healthy individuals with benign lymph nodes(benign lymph node group) diagnosed by biopsy from January 2016 to January 2019 in our hospital were retrospectively analyzed. All the selected subjects underwent the DKI examinations. Diffusion(D) and kurtosis(K) values were recorded, and were compared among head and neck lymphoma patients with different pathological types and cell sources. ROC curve was used to analyze the value of DKI in the diagnosis of head and neck lymphoma. Results: There was significant difference in D value among the three groups(F=96.380, P<0.05). D value of head and neck lymphoma group was significantly lower than that of lymph node metastasis group and benign lymph node group(P<0.05). D value of Non-Hodgkin’s lymphoma(NHL) type was significantly lower than that of Hodgkin’s lymphoma(HL) type(P<0.05). D and K values of NHL from B cells and T cells had no significant difference(P>0.05). When the D value was 1.06×10-3 mm2/s, the AUC, sensitivity and specificity of D value in the diagnosis of head and neck lymphoma was 0.801, 85.09% and 69.83%, respectively. When the D value was 0.94×10-3 mm2/s, the AUC, sensitivity and specificity of D value in the diagnosis of head and neck lymphoma was 0.817, 68.18% and 89.13%, respectively. Conclusion: The D value of magnetic resonance DKI has a high value in the diagnosis and classification of head and neck lymphoma, which can provide a reliable basis for early diagnosis of head and neck lymphoma.
高 博，王小博，潘晓晔，陈莉军. 磁共振DKI成像模式对头颈部淋巴瘤的诊断价值[J]. 中国临床医学影像杂志, 2020, 31(8): 563-567.
GAO Bo, WANG Xiao-bo, PAN Xiao-ye, CHEN Li-jun. Diagnostic value of diffusion kurtosis imaging in head and neck lymphoma. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(8): 563-567.
[1]王倩，申玉鑫，张永远，等. 脑原发淋巴瘤的影像学表现及鉴别诊断[J]. 肿瘤基础与临床，2017，30（6）：531-532.
[2]King AD, Law BK, Tang WK, et al. MRI of diffuse large B-cell non-Hodgkin’s lymphoma of the head and neck: comparison of Waldeyer’s ring and sinonasal lymphoma[J]. Eur Arch Otorhinolaryngol, 2017, 27(2): 1079-1087.
[3]王星，邹志康. 中美空军飞行学员医学选拔对照实证研究——头颈部异常[J]. 空军医学杂志，2016，32（1）：20-24.
[4]孟云，程敬亮，张勇，等. 3.0T高b值DWI在中枢神经系统淋巴瘤中的应用研究[J]. 临床放射学杂志，2016，35（5）：660-663.
[5]刘旋辉. 原发性中枢神经系统淋巴瘤常规和功能磁共振成像的特点及诊断价值分析[J]. 中国CT和MRI杂志，2018，16（11）：22-24.
[6]Shiraishi T, Chikui T, Inadomi D, et al. MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions[J]. Oral Radiol, 2016, 32(2): 98-104.
[7]郝凤玲. 磁共振扩散成像技术IVIM、DTI、DKI在胶质瘤分级中的研究进展[J]. 医学影像学杂志，2018，28（12）：2104-2106.
[8]张家慧，郎宁，袁慧书. 磁共振扩散峰度成像的临床研究进展[J]. 磁共振成像，2018，9（4）：316-320.
[9]俞顺，包强，苏家威. 磁共振扩散峰度成像对腮腺肿瘤的鉴别诊断价值[J]. 放射学实践，2017，32（8）：821-826.
[10]Minosse S, Marzi S, Piludu F, et al. Correlation study between DKI and conventional DWI in brain and head and neck tumors[J]. Magn Reson Imaging, 2017, 42: 114-122.
[11]欧田田. 孙雪梅教授治疗恶性淋巴瘤临床经验浅析[J]. 河北中医，2019，41（2）：165-168.
[12]Shamloo N, Ghannadan A, Jafari M, et al. Head and Neck Lymphoma in an Iranian Population[J]. Iran J Otorhinolaryngol, 2017, 29(94): 261-267.
[13]陈翠芳，钟婧，陈韵彬，等. 功能磁共振成像在头颈部淋巴瘤中的研究进展[J]. 医学综述，2017，23（21）：4317-4321.
[14]Men Y, Sun X, Wei D, et al. Primary extranodal head and neck classical Hodgkin lymphoma: A rare clinical case report[J]. Exp Ther Med, 2016, 12(2): 1007-1011.
[15]孙俊旗，单菲菲，吴光耀，等. 磁共振弥散加权成像在鼻咽淋巴瘤与鼻咽癌鉴别诊断的价值[J]. 山西医科大学学报，2016，47（7）：665-668.
