磁共振DKI成像模式对头颈部淋巴瘤的诊断价值

doi:10.12117/jccmi.2020.08.009

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摘要目的：探讨磁共振扩散峰度成像（DKI）模式对头颈部淋巴瘤的诊断价值。方法：回顾性分析我院2016年1月—2019年1月收治的114例经活检病理确诊的头颈部淋巴瘤患者的临床资料，以此114例患者为头颈部淋巴瘤组，选取同期我院经病理确诊的合并颈部淋巴结转移的其他肿瘤患者97例为淋巴结转移组，我院体检健康者82例为良性淋巴结组。所有人均经磁共振DKI检查。比较3组扩散系数（D值）、扩散峰度（K值），不同病理分型头颈部淋巴瘤D值、K值，不同细胞来源头颈部淋巴瘤D值、K值，采用ROC曲线分析磁共振DKI对头颈部淋巴瘤的诊断价值。结果：3组D值比较有明显差异（F=96.380，P＜0.05），头颈部淋巴瘤组D值明显低于淋巴结转移组及良性淋巴结组（P＜0.05）。非霍奇金淋巴瘤（NHL）型D值显著低于霍奇金淋巴瘤（HL）型（P＜0.05）。来源于B细胞NHL与来源于T细胞NHL的D值、K值比较无明显差异（P＞0.05）。以D值为诊断指标行ROC曲线分析，当D值取1.06×10-3 mm2/s时，对头颈部淋巴瘤诊断的AUC为0.801，灵敏度为85.09%，特异度为69.83%；当D值取0.94×10-3 mm2/s时，对头颈部淋巴瘤病理分型的AUC为0.817，灵敏度为68.18%，特异度为89.13%。结论：磁共振DKI的参数D值对诊断头颈部淋巴瘤以及头颈部淋巴瘤分型具有较高价值，可为临床早期诊断头颈部淋巴瘤提供可靠依据。

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	高博
	王小博
	潘晓晔
	陈莉军

关键词 ：头颈部肿瘤, 淋巴瘤, 磁共振成像

Abstract：Objective: To investigate the diagnostic value of diffusion kurtosis imaging(DKI) in head and neck lymphoma. Methods: The clinical data of 114 cases of head and neck lymphoma(neck lymphoma group), 97 tumor patients with neck lymph node metastasis(lymph node metastasis group) and 82 healthy individuals with benign lymph nodes(benign lymph node group) diagnosed by biopsy from January 2016 to January 2019 in our hospital were retrospectively analyzed. All the selected subjects underwent the DKI examinations. Diffusion(D) and kurtosis(K) values were recorded, and were compared among head and neck lymphoma patients with different pathological types and cell sources. ROC curve was used to analyze the value of DKI in the diagnosis of head and neck lymphoma. Results: There was significant difference in D value among the three groups(F=96.380, P<0.05). D value of head and neck lymphoma group was significantly lower than that of lymph node metastasis group and benign lymph node group(P<0.05). D value of Non-Hodgkin’s lymphoma(NHL) type was significantly lower than that of Hodgkin’s lymphoma(HL) type(P<0.05). D and K values of NHL from B cells and T cells had no significant difference(P>0.05). When the D value was 1.06×10-3 mm2/s, the AUC, sensitivity and specificity of D value in the diagnosis of head and neck lymphoma was 0.801, 85.09% and 69.83%, respectively. When the D value was 0.94×10-3 mm2/s, the AUC, sensitivity and specificity of D value in the diagnosis of head and neck lymphoma was 0.817, 68.18% and 89.13%, respectively. Conclusion: The D value of magnetic resonance DKI has a high value in the diagnosis and classification of head and neck lymphoma, which can provide a reliable basis for early diagnosis of head and neck lymphoma.

Key words： Head and neck neoplasms Lymphoma Magnetic resonance imaging

收稿日期: 2020-01-13

PACS:	Ｒ739.91
	Ｒ445.2

通讯作者: 陈莉军，甘肃省人民医院放射科，730030。E-mail：1365562964@qq.com

作者简介: 高博（1986-），男，甘肃庆阳人，主治医师。E-mail：gy100495@163.com

引用本文:

高博，王小博，潘晓晔，陈莉军. 磁共振DKI成像模式对头颈部淋巴瘤的诊断价值[J]. 中国临床医学影像杂志, 2020, 31(8): 563-567.
GAO Bo, WANG Xiao-bo, PAN Xiao-ye, CHEN Li-jun. Diagnostic value of diffusion kurtosis imaging in head and neck lymphoma. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(8): 563-567.

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http://www.jccmi.com.cn/CN/10.12117/jccmi.2020.08.009 或 http://www.jccmi.com.cn/CN/Y2020/V31/I8/563

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