Correlation study of T2 signal values of deep brain gray nucleus and estimated iron content at 3.0 Tesla MR
XU Hua-zhi1, SUN Bo2, LI Jian-ce1
1. Department of Radiology, the First Affiliated Hospital of Wenzhou Medical College, Wenzhou Zhejiang 325000, China;2. Imaging Center of Neuroscience, Beijing Tiantan Hospital, Beijing 100050, China
Abstract：Objective: To study the correlation of T2 signal values of deep brain gray nucleus and estimated iron content at 3.0 Tesla magnetic resonance machine. Materials and Methods: 1192 cases of T2WI of normal brain examined at 3.0T Siemens Trio machine in Beijing Tiantan Hospital from Dec. 2004 to May 2005 were collected(including male 689, female 503, age ranged from 1 to 87 years). All cases were divided into 17 groups by five years. The signal values of red nucleus, substantia nigra, globus pallidus, putamen, caudate nucleus and the frontal cortex on T2WI were measured with Efilm workstation 2.0 measuring tools, the measurements were conducted three times. The ratios of T2 signal values of deep gray nucleus compared to the frontal cortex were calculated. Results: The ratios of red nucleus, substantia nigra, globus pallidus, putamen showed a strong linear correlation with estimated iron content(red nucleus P=0.001, r=-0.748, substantia nigra P<0.001, r= -0.863, globus pallidus P<0.001, r=-0.965, putamen P<0.001, r=-0.816). But there was no linear correlation between the ratio of caudate nucleus and the estimated iron content of that(P=0.336>0.05). Conclusion: The ratios of red nucleus, substantia nigra, globus pallidus, putamen can reflect local nonheme iron content semi-quantitatively.
许化致;孙 波;李建策. 3.0T磁共振脑深部核团T2信号值与脑铁浓度相关关系研究[J]. , 2007, 18(2): 81-84.
XU Hua-zhi;SUN Bo;LI Jian-ce. Correlation study of T2 signal values of deep brain gray nucleus and estimated iron content at 3.0 Tesla MR. , 2007, 18(2): 81-84.
2007, Vol. 18 
