Abstract:Objective: To evaluate the diagnostic accuracy for the assessment of coronary artery diseases with 64-slice CT coronary angiography. Methods: Totally 562 patients suspected of coronary artery diseases(CAD) were examined by 64-slice spiral CT, 48 of them also compared with conventional coronary angiography(CCA) regarded as the gold standard. The visibility of coronary branches was evaluated. The left main artery(LM), left anterior descending artery(LAD), circumflex artery(CX), and right coronary artery (RCA) were screened for the presence of over 50% stenosis. Results: Among the 562 patients, 48 patients were consisted with CCA. 720 coronary arteries of them can be detected. 687 coronary segments were applied for quantitative analysis. Ninty-eight lesions were found by SCTCA, 92 lesions were found by CCA. The sensitivity, specificity, positive predict values and negative predict values were 94.5%, 98.1%, 88.7%, and 99.2% respectively for the detection of coronary artery stenosis with SCTCA. Conclusion: 64-slice CTCA has excellent sensitivity and specificity in detecting coronary artery stenosis. It is a useful non-invasive method for screening coronary artery diseases, an important role in clinical diagnosis.