A preliminary study of MSCT perfusion methods in renal cell carcinoma
SUN Jian-nan1, GUO Qi-yong1, LIU Ying2, GAO Li-yuan2
1.Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China;2.CT Room, Daqing Oil Field General Hospital, Daqing Heilongjiang 163001, China
Abstract:Objective: To evaluate the application of MSCT perfusion in renal cell carcinoma. Methods: Renal cell carcinoma perfusion was performed in 19 cases with 16 row detector spiral CT, which was confirmed by operation and pathology. Contrast medium(Ultravist 300mg/I) was administered at a dose of 50ml and the rate of injection was 4ml/s. To obtain the perfusion values and maps, data were analyzed by perfusion 3 software. Results: Perfusion value for both sides of the normal kidneys was not obviously different. Compared to normal renal cortex, tumor parenchyma was enhanced obviously and the BF value of tumor was lower. PS value was positively correlated with malignant degree of carcinoma. Perfusion value in the necrotic region of carcinoma decreased significantly. Conclusion: MSCT perfusion image provides quantitative information about renal hemodynamic and could be used to evaluate microcirculation in renal cell carcinoma.