Abstract：Abstract: Objective: To determine the value of hippocampal T2 relaxation time(HCT2) on MRI for the assessment of temporal lobe epilepsy(TLE), and provide primary quantitative data to predict its operational prognosis by HCT2. Methods: Thirty-six cases of generalized epilepsy(GEP), 23 non-temporal lobe partial epilepsy(NTPE), 26 temporal lobe epilepsy(TLE) and 60 neurologically healthy people(CL) were chosen to get the HCT2 on oblique coronary MRI obtained by SE dual echo sequence, and the differences of HCT2 between different groups were analyzed. Results: The mean HCT2 of high side in TLE was 7.5518ms higher than that in CL(P=0.000), and 4.1639ms and 3.7293ms higher than that in GEP and NTPE respectively(P=0.000, 0.000). The mean HCT2 of low side in TLE, low side and high side in GEP and NTPE, were 2.7547ms, 3.1347ms, 3.2829ms, 3.4669ms, 3.9016ms higher than those in CL respectively(P=0.000, 0.000, 0.000, 0.000, 0.000). The mean HCT2 ratio of low side to high side in TLE was 0.0482, 0.0456, 0.0425 lower than those in CL, GEP and NTPE respectively(P=0.000, 0.000, 0.000). Conclusion: HCT2 of focus side in TLE is significantly higher than those in CL, GEP and NTPE. The lower HCT2 ratio of low side to high side is relatively specific change in TLE.
2009, Vol. 20 
